ea0016p784 | Thyroid | ECE2008
Glogowska Aleksandra
, Weber Ekkehard
, Los Marek
, Hoang-Vu Cuong
, Klonisch Thomas
Klonisch Thomas
The cytoplasmic domain of the membrane-anchored human EGF proform is encoded by exons 2224 and the function of this proEGFcyt is largely unkown. Stable transfectants of the human thyroid carcinoma (Ca) cell line FTC-133 were generated over-expressing (a) proEGFcyt, (b) truncated peptide version encoded by exons 22 and 23 (proEGF22.23), and (c) a natural splice version with a deletion of exon 23 and 24 (proEGFdel23). ProEGFcyt and proEGF22.23 transfectants, but not proEGF...